Assay Detail
Functional
CHEMBL702736
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Antitumor activity was evaluated in vitro on a L1210 tumor cell line
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogs of pyrrolo[1,4]benzodiazepines (PBDs)
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.85 | 5.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL85847 | — | — | 1 | 5.05 |
| CHEMBL82340 | — | — | 1 | 4.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL85847 | — | IC50 | = | 8840.0 | nM | 5.05 |
| CHEMBL82340 | — | IC50 | = | 22400.0 | nM | 4.65 |