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Assay Detail

CHEMBL702937

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for its inhibitory concentration to inhibit the growth of wild type L1210 cells and a subline ( L1210 / R81 ).
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Methotrexate analogues. 28. Synthesis and biological evaluation of new gamma-monoamides of aminopterin and methotrexate.
Rosowsky A, Bader H, Radike-Smith M, Cucchi CA, Wick MM, Freisheim JH.
J Med Chem (1986) 29 : 1703 -1709
PubMed 3462394 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.77 4.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL46140 1 4.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL46140 IC50 = 17000.0 nM 4.77