Assay Detail
Functional
CHEMBL703376
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Concentration required to decrease the growth rate to 50% of control was evaluated by determining their ability to inhibit growth of L1210 cells in vitro.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, antiproliferative, and antiviral activity of certain 4-aminopyrrolo[2,3-d]pyridazine nucleosides: an entry into a novel series of adenosine analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.81 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267099 | TUBERCIDIN | — | 1 | 7.40 |
| CHEMBL62099 | — | — | 1 | 5.40 |
| CHEMBL611541 | — | — | 1 | 4.62 |
| CHEMBL610706 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267099 | TUBERCIDIN | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL62099 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL611541 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL610706 | — | IC50 | > | 100000.0 | nM | - |