Assay Detail
Functional
CHEMBL703395
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Blockade of peak Kv1.3 potassium currents
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Potassium voltage-gated channel subfamily A member 3 (CHEMBL4818) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Alkoxypsoralens, novel nonpeptide blockers of Shaker-type K+ channels: synthesis and photoreactivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 4.38 | 4.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL342911 | — | — | 1 | 4.55 |
| CHEMBL141214 | — | — | 1 | 4.55 |
| CHEMBL141680 | — | — | 1 | 4.05 |
| CHEMBL24171 | BERGAPTEN | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL342911 | — | Kd | = | 28000.0 | nM | 4.55 |
| CHEMBL141214 | — | Kd | = | 28000.0 | nM | 4.55 |
| CHEMBL141680 | — | Kd | = | 90000.0 | nM | 4.05 |
| CHEMBL24171 | BERGAPTEN | Kd | = | 101000.0 | nM | - |