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Assay Detail

CHEMBL703692

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro inhibitory activity against murine Lewis lung tumor LL2 cell line
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type Lewis lung carcinoma
Confidence 1 — Organism
Curated By Intermediate

Target

Lewis lung carcinoma cell line (CHEMBL614088)
Type CELL-LINE
Organism Mus musculus

Publication

Synthesis, SAR, and antitumor properties of diamino-C,N-diarylpyrimidine positional isomers: inhibitors of lysophosphatidic acid acyltransferase-beta.
Gong B, Hong F, Kohm C, Jenkins S, Tulinsky J, Bhatt R, De Vries P, Singer JW, Klein P.
Bioorg Med Chem Lett (2004) 14 : 2303 -2308
PubMed 15081029 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.80 6.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL422414 1 6.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL422414 IC50 = 160.0 nM 6.80