Assay Detail
Functional
CHEMBL704177
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for its cytotoxic concentration required to inhibit the replication of human tumor nasopharynx (KB-VIN) cell lines which is drug resistant
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antitumor agents. Part 215: antitubulin effects of cytotoxic B-ring modified allocolchicinoids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.47 | 8.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL329817 | — | — | 1 | 8.04 |
| CHEMBL95224 | — | — | 1 | 7.21 |
| CHEMBL300734 | — | — | 1 | 7.17 |
| CHEMBL107 | COLCHICINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL329817 | — | IC50 | = | 9.1 | nM | 8.04 |
| CHEMBL95224 | — | IC50 | = | 62.0 | nM | 7.21 |
| CHEMBL300734 | — | IC50 | = | 68.0 | nM | 7.17 |
| CHEMBL107 | COLCHICINE | IC50 | > | 100.0 | nM | - |