Assay Detail
Functional
CHEMBL704308
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The compound was tested for growth inhibitory activity against L1210/0 tumor cell lines
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel pyrimidine and purine derivatives of L-ascorbic acid: synthesis and biological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.17 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92041 | — | — | 1 | 5.70 |
| CHEMBL419504 | — | — | 1 | 5.39 |
| CHEMBL327570 | — | — | 1 | 5.29 |
| CHEMBL328116 | — | — | 1 | 5.12 |
| CHEMBL90871 | — | — | 1 | 5.12 |
| CHEMBL88616 | — | — | 1 | 4.94 |
| CHEMBL88434 | — | — | 1 | 4.91 |
| CHEMBL91024 | — | — | 1 | 4.89 |
| CHEMBL315331 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92041 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL419504 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL327570 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL328116 | — | IC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL90871 | — | IC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL88616 | — | IC50 | = | 11600.0 | nM | 4.94 |
| CHEMBL88434 | — | IC50 | = | 12200.0 | nM | 4.91 |
| CHEMBL91024 | — | IC50 | = | 12900.0 | nM | 4.89 |
| CHEMBL315331 | — | IC50 | = | 110000.0 | nM | - |