Assay Detail
Functional
CHEMBL704560
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Tested for inhibition of L1210 cell growth by the compound after 48 hr
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthetic polyamine analogues as antineoplastics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.71 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18111 | — | — | 1 | 5.52 |
| CHEMBL18794 | BIS(ETHYL)SPERMINE | — | 1 | 5.00 |
| CHEMBL18083 | — | — | 1 | 4.30 |
| CHEMBL18610 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18111 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL18794 | BIS(ETHYL)SPERMINE | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL18083 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL18610 | — | IC50 | = | 100000.0 | nM | 4.00 |