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Assay Detail

CHEMBL704719

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was tested in vitro for cytotoxic activity against L1210 cell line (mouse leukemia)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

An exceptionally potent analog of sandramycin
Boger DL, Chen J
Bioorg Med Chem Lett (1997) 7 : 919 -922
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 10.20 10.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL441158 1 10.70
CHEMBL265841 1 9.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL441158 IC50 = 0.02 nM 10.70
CHEMBL265841 IC50 = 0.2 nM 9.70