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Assay Detail

CHEMBL704753

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration against L1210 cells on 96 hr incubation.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

The role of charge in polyamine analogue recognition.
Bergeron RJ, McManis JS, Weimar WR, Schreier KM, Gao F, Wu Q, Ortiz-Ocasio J, Luchetta GR, Porter C, Vinson JR.
J Med Chem (1995) 38 : 2278 -2285
PubMed 7608892 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.87 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL72019 1 7.00
CHEMBL310220 1 6.52
CHEMBL73459 1 4.10
CHEMBL74511 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL72019 IC50 = 100.0 nM 7.00
CHEMBL310220 IC50 = 300.0 nM 6.52
CHEMBL73459 IC50 = 80000.0 nM 4.10
CHEMBL74511 IC50 > 100000.0 nM -