Assay Detail

CHEMBL704754

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Functional

Inhibitory concentration against L1210 cells on 96h incubation.

ChEMBL ↗

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Target

L1210 (CHEMBL386) ↗

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L1210 (CHEMBL386) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target L1210

CHEMBL386

Anchored from Assay target.

Protein identity L1210

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Mus musculus
Cell Type	L1210
Confidence	1 — Organism
Curated By	Intermediate

Target

L1210 (CHEMBL386) ↗

Type	CELL-LINE
Organism	Mus musculus

Publication

The role of charge in polyamine analogue recognition.

Bergeron RJ, McManis JS, Weimar WR, Schreier KM, Gao F, Wu Q, Ortiz-Ocasio J, Luchetta GR, Porter C, Vinson JR.
J Med Chem (1995) 38 : 2278 -2285
PubMed 7608892 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	6.70	6.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL18794	BIS(ETHYL)SPERMINE	—	1	6.70
CHEMBL306840	—	—	1	-

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL18794	BIS(ETHYL)SPERMINE	IC50	=	200.0	nM	6.70
CHEMBL306840	—	IC50	>	100000.0	nM	-