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Assay Detail

CHEMBL704761

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration on murine leukemia L1210/0 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Antiviral enantiomeric preference for 5'-noraristeromycin.
Siddiqi SM, Chen X, Schneller SW, Ikeda S, Snoeck R, Andrei G, Balzarini J, De Clercq E.
J Med Chem (1994) 37 : 551 -554
PubMed 8120872 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.91 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL129014 NORARISTEROMYCIN 1 6.30
CHEMBL8275 1 6.20
CHEMBL2051948 1 5.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL129014 NORARISTEROMYCIN IC50 = 500.0 nM 6.30
CHEMBL8275 IC50 = 630.0 nM 6.20
CHEMBL2051948 IC50 = 5700.0 nM 5.24