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Assay Detail

CHEMBL704836

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for the growth inhibition of L1210 cell at a duration of 96 h
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Polyamine-iron chelator conjugate.
Bergeron RJ, McManis JS, Franklin AM, Yao H, Weimar WR.
J Med Chem (2003) 46 : 5478 -5483
PubMed 14640556 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.43 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL150911 1 6.70
CHEMBL82888 1 6.48
CHEMBL70927 DEFERIPRONE 4.0 1 4.26
CHEMBL284260 1 4.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL150911 IC50 = 200.0 nM 6.70
CHEMBL82888 IC50 = 330.0 nM 6.48
CHEMBL70927 DEFERIPRONE IC50 = 55000.0 nM 4.26
CHEMBL284260 IC50 = 55000.0 nM 4.26