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Assay Detail

CHEMBL705193

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration of compound against growth of human melanoma cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type LOX IMVI
Confidence 1 — Organism
Curated By Intermediate

Target

LOX IMVI (CHEMBL614096)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and evaluation of novel rhodacyanine dyes that exhibit antitumor activity.
Kawakami M, Koya K, Ukai T, Tatsuta N, Ikegawa A, Ogawa K, Shishido T, Chen LB.
J Med Chem (1997) 40 : 3151 -3160
PubMed 9379434 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 7.50 7.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL108793 1 7.70
CHEMBL106653 1 7.40
CHEMBL108063 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL108793 IC50 = 20.0 nM 7.70
CHEMBL106653 IC50 = 40.0 nM 7.40
CHEMBL108063 IC50 = 40.0 nM 7.40