Assay Detail
Functional
CHEMBL705264
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Dose level for 50% inhibition of L1210 cell growth was measured after 24 hr
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, molecular modeling, DNA binding, and antitumor properties of some substituted amidoanthraquinones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.31 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL141831 | — | — | 1 | 6.22 |
| CHEMBL169167 | — | — | 1 | 5.10 |
| CHEMBL169281 | — | — | 1 | 5.10 |
| CHEMBL171228 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL141831 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL169167 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL169281 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL171228 | — | IC50 | = | 16000.0 | nM | 4.80 |