Assay Detail
Functional
CHEMBL705265
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Dose level for 50% inhibition of L1210 cell growth was measured after 24 h.
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, molecular modeling, DNA binding, and antitumor properties of some substituted amidoanthraquinones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.11 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL58 | MITOXANTRONE | 4.0 | 1 | 7.00 |
| CHEMBL359443 | — | — | 1 | 6.22 |
| CHEMBL352484 | — | — | 1 | 6.22 |
| CHEMBL169172 | — | — | 1 | 6.00 |
| CHEMBL171428 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL58 | MITOXANTRONE | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL359443 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL352484 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL169172 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL171428 | — | IC50 | = | 8000.0 | nM | 5.10 |