Assay Detail
Functional
CHEMBL705274
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Growth uM after 48 hours
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.66 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL77101 | DIETHYLHOMOSPERMINE | 1.0 | 1 | 6.70 |
| CHEMBL77102 | — | — | 1 | 6.00 |
| CHEMBL80386 | IVOSPEMIN | 3.0 | 1 | 5.70 |
| CHEMBL77818 | — | — | 1 | 5.52 |
| CHEMBL76840 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL77101 | DIETHYLHOMOSPERMINE | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL77102 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL80386 | IVOSPEMIN | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL77818 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL76840 | — | IC50 | = | 40000.0 | nM | 4.40 |