Assay Detail
Functional
CHEMBL705275
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth uM after 96 hours
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.68 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL80386 | IVOSPEMIN | 3.0 | 1 | 7.22 |
| CHEMBL77101 | DIETHYLHOMOSPERMINE | 1.0 | 1 | 7.16 |
| CHEMBL76840 | — | — | 1 | 7.10 |
| CHEMBL77102 | — | — | 1 | 6.22 |
| CHEMBL77818 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL80386 | IVOSPEMIN | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL77101 | DIETHYLHOMOSPERMINE | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL76840 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL77102 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL77818 | — | IC50 | = | 2000.0 | nM | 5.70 |