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Assay Detail

CHEMBL705366

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Tested for growth inhibition of Lactobacillus casei (ATCC 7649)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Lacticaseibacillus casei
Confidence 1 — Organism
Curated By Intermediate

Target

Lacticaseibacillus casei (CHEMBL613075)
Type ORGANISM
Organism Lacticaseibacillus casei

Publication

Synthesis and biological evaluation of 8-deazahomofolic acid and its tetrahydro derivative.
DeGraw JI, Colwell WT, Brown VH, Sato M, Kisliuk RL, Gaumont Y, Thorndike J, Sirotnak FM.
J Med Chem (1988) 31 : 150 -153
PubMed 3121855 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 10.30 10.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL34259 METHOTREXATE 4.0 1 10.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL34259 METHOTREXATE IC50 = 0.05 nM 10.30