Assay Detail
Functional
CHEMBL705370
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of dTMP synthetase in the absence of CH2-H4 folate Lactobacillus casei
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Lacticaseibacillus casei |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Mechanism of action of 2',5-difluoro-1-arabinosyluracil.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.95 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1236538 | — | — | 1 | 6.72 |
| CHEMBL211312 | DEOXYURIDINE MONOPHOSPHATE | — | 1 | 5.64 |
| CHEMBL253954 | — | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1236538 | — | Ki | = | 190.0 | nM | 6.72 |
| CHEMBL211312 | DEOXYURIDINE MONOPHOSPHATE | Ki | = | 2300.0 | nM | 5.64 |
| CHEMBL253954 | — | Ki | = | 3300.0 | nM | 5.48 |