Assay Detail
Binding
CHEMBL705402
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Compound was tested for inhibition of human leucocyte elastase (HLE)
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.73 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2370179 | — | — | 1 | 7.52 |
| CHEMBL2370192 | — | — | 1 | 7.22 |
| CHEMBL2370184 | — | — | 1 | 7.00 |
| CHEMBL2370193 | — | — | 1 | 5.17 |
| CHEMBL2370189 | — | — | 1 | - |
| CHEMBL310738 | — | — | 1 | - |
| CHEMBL306027 | — | — | 1 | - |
| CHEMBL2370171 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2370179 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL2370192 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL2370184 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL2370193 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL2370189 | — | IC50 | = | 120000.0 | nM | - |
| CHEMBL310738 | — | IC50 | < | 60.0 | nM | - |
| CHEMBL306027 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL2370171 | — | IC50 | > | 1000000.0 | nM | - |