Assay Detail
Functional
CHEMBL705879
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MCF-7 cancer cell proliferation
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Estrogen receptor ligands. Part 6: Synthesis and binding affinity of dihydrobenzodithiins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.84 | 7.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL124482 | — | — | 1 | 7.17 |
| CHEMBL331996 | — | — | 1 | 6.95 |
| CHEMBL123025 | — | — | 1 | 6.94 |
| CHEMBL126164 | — | — | 1 | 6.91 |
| CHEMBL125362 | — | — | 1 | 6.82 |
| CHEMBL341367 | — | — | 1 | 6.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL124482 | — | IC50 | = | 67.0 | nM | 7.17 |
| CHEMBL331996 | — | IC50 | = | 112.0 | nM | 6.95 |
| CHEMBL123025 | — | IC50 | = | 114.0 | nM | 6.94 |
| CHEMBL126164 | — | IC50 | = | 123.0 | nM | 6.91 |
| CHEMBL125362 | — | IC50 | = | 152.0 | nM | 6.82 |
| CHEMBL341367 | — | IC50 | = | 564.0 | nM | 6.25 |