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Assay Detail

CHEMBL705880

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of MCF-7 cancer cell proliferation; Average of 2 measurements
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Expert

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Estrogen receptor ligands. Part 6: Synthesis and binding affinity of dihydrobenzodithiins.
Tan Q, Birzin ET, Chan W, Yang YT, Pai LY, Hayes EC, DaSilva CA, DiNinno F, Rohrer SP, Schaeffer JM, Hammond ML.
Bioorg Med Chem Lett (2004) 14 : 3753 -3755
PubMed 15203156 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.40 9.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL93705 1 9.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL93705 IC50 = 0.4 nM 9.40