Assay Detail
Functional
CHEMBL706078
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Compound was tested for inhibitory activity against the in vitro growth of Murine leukemia L1210 cells using MTT assay.
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Nucleosides and nucleotides. 180. Synthesis and antitumor activity of nucleosides that have a hydroxylamino group instead of a hydroxyl group at the 2'- or 3'-position of the sugar moiety.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.85 | 5.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL150007 | — | — | 1 | 5.44 |
| CHEMBL341869 | — | — | 1 | 5.39 |
| CHEMBL358259 | — | — | 1 | 4.56 |
| CHEMBL149078 | — | — | 1 | 4.46 |
| CHEMBL149762 | — | — | 1 | 4.42 |
| CHEMBL149614 | — | — | 1 | - |
| CHEMBL146199 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL150007 | — | IC50 | = | 3630.0 | nM | 5.44 |
| CHEMBL341869 | — | IC50 | = | 4030.0 | nM | 5.39 |
| CHEMBL358259 | — | IC50 | = | 27500.0 | nM | 4.56 |
| CHEMBL149078 | — | IC50 | = | 34500.0 | nM | 4.46 |
| CHEMBL149762 | — | IC50 | = | 37700.0 | nM | 4.42 |
| CHEMBL149614 | — | IC50 | > | 300000.0 | nM | - |
| CHEMBL146199 | — | IC50 | > | 300000.0 | nM | - |