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Assay Detail

CHEMBL706103

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Tested for inhibitory activity against murine cell line L12110 leukemia, a strain resistant to doxorubicin using MTT assay.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Analogues of amonafide and azonafide with novel ring systems.
Sami SM, Dorr RT, Alberts DS, Sólyom AM, Remers WA.
J Med Chem (2000) 43 : 3067 -3073
PubMed 10956214 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.43 6.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL105801 1 6.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL105801 IC50 = 367.0 nM 6.43