Assay Detail
Binding
CHEMBL706151
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Inhibition of binding to L-type [Ca2+] channel
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Voltage-gated L-type calcium channel (CHEMBL2095229) ↗| Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
Publication
Phenyl-glycinol based NK1 receptor antagonists towards the minimum pharmacophore
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.94 | 6.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92818 | — | — | 1 | 6.24 |
| CHEMBL329105 | — | — | 1 | 5.64 |
| CHEMBL327765 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92818 | — | IC50 | = | 580.0 | nM | 6.24 |
| CHEMBL329105 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL327765 | — | IC50 | > | 10000.0 | nM | - |