Assay Detail
Functional
CHEMBL706327
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Compound was tested in vitro for cytotoxicity against MCF-7 cell lines from Mammary adenocarcinoma.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Nucleosides and nucleotides. 180. Synthesis and antitumor activity of nucleosides that have a hydroxylamino group instead of a hydroxyl group at the 2'- or 3'-position of the sugar moiety.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.19 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL347737 | — | — | 1 | 5.89 |
| CHEMBL341869 | — | — | 1 | 5.16 |
| CHEMBL149829 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL347737 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL341869 | — | IC50 | = | 6910.0 | nM | 5.16 |
| CHEMBL149829 | — | IC50 | = | 30300.0 | nM | 4.52 |