Assay Detail
Binding
CHEMBL706546
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Inhibition of leucine aminopeptidase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Inhibition of aminopeptidases by peptides containing ketomethylene and hydroxyethylene amide bond replacements.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.18 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29292 | UBENIMEX | 2.0 | 1 | 7.70 |
| CHEMBL28650 | AMASTATIN | — | 1 | 6.66 |
| CHEMBL282583 | — | — | 1 | - |
| CHEMBL281437 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29292 | UBENIMEX | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL28650 | AMASTATIN | Ki | = | 220.0 | nM | 6.66 |
| CHEMBL282583 | — | Ki | > | 100.0 | ug ml-1 | - |
| CHEMBL281437 | — | Ki | > | 100.0 | ug ml-1 | - |