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Assay Detail

CHEMBL706973

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration of lipid peroxidation (LPO).
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Thiazoloindans and thiazolobenzopyrans: a novel class of orally active central dopamine (partial) agonists.
van Vliet LA, Rodenhuis N, Wikström H, Pugsley TA, Serpa KA, Meltzer LT, Heffner TG, Wise LD, Lajiness ME, Huff RM, Svensson K, Haenen GR, Bast A.
J Med Chem (2000) 43 : 3549 -3557
PubMed 11000009 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.59 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL332677 1 5.30
CHEMBL118636 1 4.52
CHEMBL116372 1 4.30
CHEMBL325710 1 4.22
CHEMBL118637 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL332677 IC50 = 5000.0 nM 5.30
CHEMBL118636 IC50 = 30000.0 nM 4.52
CHEMBL116372 IC50 = 50000.0 nM 4.30
CHEMBL325710 IC50 = 60000.0 nM 4.22
CHEMBL118637 IC50 > 100000.0 nM -