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Assay Detail

CHEMBL707168

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for the cytotoxicity against L1210 cells in presence of coformycin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Synthesis and biochemical properties of 8-amino-6-fluoro-9-beta-D-ribofuranosyl-9H-purine.
Secrist JA, Bennett LL, Allan PW, Rose LM, Chang CH, Montgomery JA.
J Med Chem (1986) 29 : 2069 -2074
PubMed 3489838 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.60 6.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1580 PENTOSTATIN 4.0 1 6.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1580 PENTOSTATIN IC50 = 250.0 nM 6.60