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Assay Detail

CHEMBL707226

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of growth of Lactobacillus casei
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Lacticaseibacillus casei
Confidence 1 — Organism
Curated By Intermediate

Target

Lacticaseibacillus casei (CHEMBL613075)
Type ORGANISM
Organism Lacticaseibacillus casei

Publication

Folate analogues. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds.
Patil SD, Jones C, Nair MG, Galivan J, Maley F, Kisliuk RL, Gaumont Y, Duch D, Ferone R.
J Med Chem (1989) 32 : 1284 -1289
PubMed 2542557 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.53 9.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL422395 1 9.40
CHEMBL25889 1 7.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL422395 IC50 = 0.4 nM 9.40
CHEMBL25889 IC50 = 22.0 nM 7.66