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Assay Detail

CHEMBL707302

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro growth inhibition against L1210 murine leukemia cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Phenyl selenones: alkyl transfer by selenium-carbon bond cleavage.
Kang SI, Spears CP.
J Med Chem (1990) 33 : 1544 -1547
PubMed 2342050 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 8 5.83 6.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL37569 1 6.44
CHEMBL38761 1 6.26
CHEMBL38893 1 6.05
CHEMBL39437 1 5.92
CHEMBL288134 1 5.64
CHEMBL290487 1 5.52
CHEMBL39469 BENZENE SELENOIC ACID 1 5.52
CHEMBL288743 1 5.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL37569 IC50 = 360.0 nM 6.44
CHEMBL38761 IC50 = 550.0 nM 6.26
CHEMBL38893 IC50 = 900.0 nM 6.05
CHEMBL39437 IC50 = 1200.0 nM 5.92
CHEMBL288134 IC50 = 2300.0 nM 5.64
CHEMBL290487 IC50 = 3000.0 nM 5.52
CHEMBL39469 BENZENE SELENOIC ACID IC50 = 3000.0 nM 5.52
CHEMBL288743 IC50 = 5000.0 nM 5.30