Assay Detail
Functional
CHEMBL707544
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Percent agonistic activity for estrogen-induced pS2 expression in MCF-7 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
A novel estrogen receptor ligand template.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 9.35 | 11.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL135 | ESTRADIOL | 4.0 | 1 | 11.00 |
| CHEMBL294889 | — | — | 1 | 7.70 |
| CHEMBL57150 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL135 | ESTRADIOL | EC50 | = | 0.01 | nM | 11.00 |
| CHEMBL294889 | — | EC50 | = | 20.0 | nM | 7.70 |
| CHEMBL57150 | — | EC50 | < | 10.0 | nM | - |