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Assay Detail

CHEMBL707635

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Functional
In vitro cytotoxicity activity against MCF7, by colony forming assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7S
Confidence 1 — Organism
Curated By Intermediate

Target

MCF7S (CHEMBL614328)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and in vitro evaluation of quaternary ammonium derivatives of chlorambucil and melphalan, anticancer drugs designed for the chemotherapy of chondrosarcoma.
Giraud I, Rapp M, Maurizis JC, Madelmont JC.
J Med Chem (2002) 45 : 2116 -2119
PubMed 11985479 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.05 6.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL538105 1 6.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL538105 IC50 = 900.0 nM 6.05