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Assay Detail

CHEMBL707751

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro cytotoxicity against MDA 231 human breast cancer cell line with EGFR positive erbB3 positive
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Expert

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo.
Shi DF, Bradshaw TD, Wrigley S, McCall CJ, Lelieveld P, Fichtner I, Stevens MF.
J Med Chem (1996) 39 : 3375 -3384
PubMed 8765521 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.77 7.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL93118 1 7.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL93118 IC50 = 17.0 nM 7.77