Assay Detail
Functional
CHEMBL707768
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for growth inhibitory activity against MCF-7 tumor cell lines
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel pyrimidine and purine derivatives of L-ascorbic acid: synthesis and biological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.36 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL91024 | — | — | 1 | 4.70 |
| CHEMBL88616 | — | — | 1 | 4.40 |
| CHEMBL328116 | — | — | 1 | 4.40 |
| CHEMBL92041 | — | — | 1 | 4.40 |
| CHEMBL88434 | — | — | 1 | 4.22 |
| CHEMBL327570 | — | — | 1 | 4.22 |
| CHEMBL90871 | — | — | 1 | 4.16 |
| CHEMBL419504 | — | — | 1 | - |
| CHEMBL315331 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL91024 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL88616 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL328116 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL92041 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL88434 | — | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL327570 | — | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL90871 | — | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL419504 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL315331 | — | IC50 | > | 100000.0 | nM | - |