Assay Detail
Functional
CHEMBL707770
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested in vitro for its antitumor activity against human breast cell line MCF-7
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antitumour benzothiazoles. Part 10: the synthesis and antitumour activity of benzothiazole substituted quinol derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.70 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL150072 | — | — | 1 | 6.64 |
| CHEMBL444004 | — | — | 1 | 6.55 |
| CHEMBL424318 | — | — | 1 | 6.51 |
| CHEMBL150016 | — | — | 1 | 6.29 |
| CHEMBL356615 | — | — | 1 | 6.25 |
| CHEMBL146035 | — | — | 1 | 5.75 |
| CHEMBL149623 | — | — | 1 | 4.72 |
| CHEMBL149322 | — | — | 1 | 4.29 |
| CHEMBL47875 | — | — | 1 | 4.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL150072 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL444004 | — | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL424318 | — | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL150016 | — | IC50 | = | 510.0 | nM | 6.29 |
| CHEMBL356615 | — | IC50 | = | 560.0 | nM | 6.25 |
| CHEMBL146035 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL149623 | — | IC50 | = | 19100.0 | nM | 4.72 |
| CHEMBL149322 | — | IC50 | = | 51800.0 | nM | 4.29 |
| CHEMBL47875 | — | IC50 | = | 53400.0 | nM | 4.27 |