Assay Detail
Functional
CHEMBL707772
Review assay metadata, readout intent, target linkage, and publication context from the same page.
compound was tested in vitro for inhibition activity against a sensitive human breast carcinoma line cells.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Doxoform and Daunoform: anthracycline-formaldehyde conjugates toxic to resistant tumor cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.64 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL406294 | DOXOFORM | — | 1 | 8.70 |
| CHEMBL429955 | DAUNOFORM | — | 1 | 8.10 |
| CHEMBL178 | DAUNORUBICIN | 4.0 | 1 | 7.22 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL406294 | DOXOFORM | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL429955 | DAUNOFORM | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL178 | DAUNORUBICIN | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 300.0 | nM | 6.52 |