Assay Detail
Functional
CHEMBL707835
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The compound was tested for the cytotoxicity against L1210 cell lines
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
9-substituted acridine derivatives with long half-life and potent antitumor activity: synthesis and structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.09 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL321473 | — | — | 1 | 7.80 |
| CHEMBL430884 | — | — | 1 | 7.55 |
| CHEMBL422252 | — | — | 1 | 7.47 |
| CHEMBL444329 | — | — | 1 | 7.35 |
| CHEMBL109928 | — | — | 1 | 7.01 |
| CHEMBL326274 | — | — | 1 | 6.48 |
| CHEMBL109468 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL321473 | — | IC50 | = | 16.0 | nM | 7.80 |
| CHEMBL430884 | — | IC50 | = | 28.0 | nM | 7.55 |
| CHEMBL422252 | — | IC50 | = | 34.0 | nM | 7.47 |
| CHEMBL444329 | — | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL109928 | — | IC50 | = | 98.0 | nM | 7.01 |
| CHEMBL326274 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL109468 | — | IC50 | = | 990.0 | nM | 6.00 |