Assay Detail
Functional
CHEMBL708162
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative effect against continuous human leukemia cell lines and peripheral blood cells from patients with acute myeloid leukemia was determined; (0.1 to 1 nM)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Blood |
| Cell Type | Panel leukemia (Carcinoma cell lines) |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and in vitro cytotoxicity of diastereoisomerically modified dolastatin 15 analogues
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 10.00 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL35769 | DOLASTATIN 15 | — | 1 | 10.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL35769 | DOLASTATIN 15 | IC50 | = | 0.1 | nM | 10.00 |