Assay Detail
Functional
CHEMBL708635
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Inhibitory concentration of compound against the growth of the L1210 cell line at 48 hr
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.27 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL77102 | — | — | 1 | 6.00 |
| CHEMBL77818 | — | — | 1 | 5.52 |
| CHEMBL84136 | — | — | 1 | 5.35 |
| CHEMBL33387 | — | — | 1 | 4.80 |
| CHEMBL44083 | BIS(ETHYL)NORSPERMINE | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL77102 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL77818 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL84136 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL33387 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL44083 | BIS(ETHYL)NORSPERMINE | IC50 | = | 20000.0 | nM | 4.70 |