Assay Detail
Functional
CHEMBL708637
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity of compound measured against L1210 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Effect of polyamine analogues on hypusine content in JURKAT T-cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.29 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL34476 | — | — | 1 | 5.85 |
| CHEMBL77101 | DIETHYLHOMOSPERMINE | 1.0 | 1 | 5.70 |
| CHEMBL35633 | — | — | 1 | 4.85 |
| CHEMBL44083 | BIS(ETHYL)NORSPERMINE | — | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL34476 | — | Ki | = | 1400.0 | nM | 5.85 |
| CHEMBL77101 | DIETHYLHOMOSPERMINE | Ki | = | 2000.0 | nM | 5.70 |
| CHEMBL35633 | — | Ki | = | 14000.0 | nM | 4.85 |
| CHEMBL44083 | BIS(ETHYL)NORSPERMINE | Ki | = | 17000.0 | nM | 4.77 |