Assay Detail
Functional
CHEMBL708639
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration inhibiting radiolabeled spermidine transport in L1210 cells.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
The role of charge in polyamine analogue recognition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.28 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18794 | BIS(ETHYL)SPERMINE | — | 1 | 5.80 |
| CHEMBL72019 | — | — | 1 | 5.31 |
| CHEMBL310220 | — | — | 1 | 4.74 |
| CHEMBL73459 | — | — | 1 | - |
| CHEMBL74511 | — | — | 1 | - |
| CHEMBL306840 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18794 | BIS(ETHYL)SPERMINE | Ki | = | 1600.0 | nM | 5.80 |
| CHEMBL72019 | — | Ki | = | 4900.0 | nM | 5.31 |
| CHEMBL310220 | — | Ki | = | 18100.0 | nM | 4.74 |
| CHEMBL73459 | — | Ki | > | 500000.0 | nM | - |
| CHEMBL74511 | — | Ki | > | 500000.0 | nM | - |
| CHEMBL306840 | — | Ki | = | 285000.0 | nM | - |