Assay Detail
Functional
CHEMBL708641
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against leucine-preferring transport system (system L) was determined in murine leukemia L1210 cell lines
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Selective cytotoxicity of a system L specific amino acid nitrogen mustard.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.06 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8708 | — | — | 1 | 5.30 |
| CHEMBL345930 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8708 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL345930 | — | Ki | = | 15200.0 | nM | 4.82 |