Assay Detail
Functional
CHEMBL708789
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for cytostatic activity against murine leukemia L1210 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
5'-Phosphoramidates and 5'-diphosphates of 2'-O-allyl-beta-D-arabinofuranosyluracil, -cytosine, and -adenine: inhibition of ribonucleotide reductase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.42 | 4.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3142861 | — | — | 1 | 4.42 |
| CHEMBL3142860 | — | — | 1 | - |
| CHEMBL3142859 | — | — | 1 | - |
| CHEMBL3142858 | — | — | 1 | - |
| CHEMBL3142862 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3142861 | — | IC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL3142860 | — | IC50 | > | 500000.0 | nM | - |
| CHEMBL3142859 | — | IC50 | = | 181000.0 | nM | - |
| CHEMBL3142858 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL3142862 | — | IC50 | > | 200000.0 | nM | - |