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Assay Detail

CHEMBL708859

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for cytotoxicity against leukemic MOLT-4 cell lines
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MOLT-4
Confidence 1 — Organism
Curated By Intermediate

Target

MOLT-4 (CHEMBL614177)
Type CELL-LINE
Organism Homo sapiens

Publication

New aza-thioxanthones: Synthesis and cytotoxicity
Varvaresou A, Tsotinis A, Papadaki-Valiraki A, Siatra-Papastaikoudi T
Bioorg Med Chem Lett (1996) 6 : 861 -864
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 5.49 5.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL355342 1 5.72
CHEMBL355131 1 5.59
CHEMBL171167 1 5.57
CHEMBL355207 1 5.47
CHEMBL354332 1 5.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL355342 IC50 = 1910.0 nM 5.72
CHEMBL355131 IC50 = 2560.0 nM 5.59
CHEMBL171167 IC50 = 2690.0 nM 5.57
CHEMBL355207 IC50 = 3420.0 nM 5.47
CHEMBL354332 IC50 = 7770.0 nM 5.11