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Assay Detail

CHEMBL708891

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of the necrosis induced by compound in breast cancer MCF-7 cell line
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Intermediate

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis of analogues of a potent antitumor saponin OSW-1.
Morzycki JW, Wojtkielewicz A, Wołczyński S.
Bioorg Med Chem Lett (2004) 14 : 3323 -3326
PubMed 15149699 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.16 5.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL375269 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL375269 IC50 = 7000.0 nM 5.16