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Assay Detail

CHEMBL708935

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for the inhibitory activity of L1210 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Application of the three-dimensional structures of protein target molecules in structure-based drug design.
Greer J, Erickson JW, Baldwin JJ, Varney MD.
J Med Chem (1994) 37 : 1035 -1054
PubMed 8164249 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 6.25 6.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL9671 1 6.82
CHEMBL9440 METESIND 2.0 1 6.52
CHEMBL275685 1 6.42
CHEMBL9728 1 5.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL9671 IC50 = 150.0 nM 6.82
CHEMBL9440 METESIND IC50 = 300.0 nM 6.52
CHEMBL275685 IC50 = 380.0 nM 6.42
CHEMBL9728 IC50 = 6000.0 nM 5.22