Assay Detail
Functional
CHEMBL708952
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Compound was tested for inhibition of L1210 cells growth in culture.
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological activity of 3- and 5-amino derivatives of pyridine-2-carboxaldehyde thiosemicarbazone.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 5.58 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL86910 | — | — | 1 | 5.96 |
| CHEMBL315999 | — | — | 1 | 5.85 |
| CHEMBL87471 | — | — | 1 | 5.82 |
| CHEMBL85661 | — | — | 1 | 5.68 |
| CHEMBL314693 | — | — | 1 | 5.62 |
| CHEMBL313203 | — | — | 1 | 5.60 |
| CHEMBL86188 | — | — | 1 | 5.47 |
| CHEMBL82809 | — | — | 1 | 5.36 |
| CHEMBL86963 | — | — | 1 | 5.29 |
| CHEMBL420050 | — | — | 1 | 5.11 |
| CHEMBL85181 | — | — | 1 | - |
| CHEMBL87996 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL86910 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL315999 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL87471 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL85661 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL314693 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL313203 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL86188 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL82809 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL86963 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL420050 | — | IC50 | = | 7800.0 | nM | 5.11 |
| CHEMBL85181 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL87996 | — | IC50 | > | 10000.0 | nM | - |