Assay Detail
Functional
CHEMBL708959
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Compound was tested for potency against multidrug-resistant murine leukemia L1210 cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
1,4-disubstituted anthracene antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.27 | 7.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25336 | BISANTRENE | 3.0 | 1 | 7.31 |
| CHEMBL22696 | — | — | 1 | 5.58 |
| CHEMBL125698 | — | — | 1 | 5.55 |
| CHEMBL287188 | — | — | 1 | 5.48 |
| CHEMBL125332 | — | — | 1 | 5.38 |
| CHEMBL121864 | — | — | 1 | 4.36 |
| CHEMBL332153 | — | — | 1 | 4.28 |
| CHEMBL333690 | — | — | 1 | 4.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25336 | BISANTRENE | IC50 | = | 49.0 | nM | 7.31 |
| CHEMBL22696 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL125698 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL287188 | — | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL125332 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL121864 | — | IC50 | = | 44000.0 | nM | 4.36 |
| CHEMBL332153 | — | IC50 | = | 52000.0 | nM | 4.28 |
| CHEMBL333690 | — | IC50 | = | 63000.0 | nM | 4.20 |